Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers

Wound healing is a complex physiological process that repairs a skin lesion and produces fibrous tissue. In some cases, this process can lead to hypertrophic scars (HS) or keloid scars (KS), for which the pathophysiology remains poorly understood. Previous studies have reported the presence of oncos...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Huguier, Vincent, Giot, Jean-Philippe, Simonneau, Marie, Levillain, Pierre, Charreau, Sandrine, Garcia, Martine, Jégou, Jean-François, Bodet, Charles, Morel, Franck, Lecron, Jean-Claude, Favot, Laure
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376164/
https://ncbi.nlm.nih.gov/pubmed/30765798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38572-0
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items