Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers

Wound healing is a complex physiological process that repairs a skin lesion and produces fibrous tissue. In some cases, this process can lead to hypertrophic scars (HS) or keloid scars (KS), for which the pathophysiology remains poorly understood. Previous studies have reported the presence of oncos...

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Udgivet i:Sci Rep
Main Authors: Huguier, Vincent, Giot, Jean-Philippe, Simonneau, Marie, Levillain, Pierre, Charreau, Sandrine, Garcia, Martine, Jégou, Jean-François, Bodet, Charles, Morel, Franck, Lecron, Jean-Claude, Favot, Laure
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376164/
https://ncbi.nlm.nih.gov/pubmed/30765798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38572-0
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