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A Model for Adult Organ Resizing Demonstrates Stem Cell Scaling through a Tunable Commitment Rate

Many adult organs grow or shrink to accommodate different physiological demands. Often, as total cell number changes, stem cell number changes proportionally in a phenomenon called “stem cell scaling”. The cellular behaviors that give rise to scaling are unknown. Here we study two complementary theo...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Du, XinXin, O’Brien, Lucy Erin, Riedel-Kruse, Ingmar Hans
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510814/
https://ncbi.nlm.nih.gov/pubmed/28700915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.040
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