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Novel Stable Isotope Analyses Demonstrate Significant Rates of Glucose Cycling in Mouse Pancreatic Islets

A polymorphism located in the G6PC2 gene, which encodes an islet-specific glucose-6-phosphatase catalytic subunit, is the most important common determinant of variations in fasting blood glucose (FBG) levels in humans. Studies of G6pc2 knockout (KO) mice suggest that G6pc2 represents a negative regu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes
Prif Awduron: Wall, Martha L., Pound, Lynley D., Trenary, Irina, O’Brien, Richard M., Young, Jamey D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439557/
https://ncbi.nlm.nih.gov/pubmed/25552595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0745
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