Tumor Necrosis Factor dynamically regulates the mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes

During rheumatoid arthritis (RA), Tumor Necrosis Factor (TNF) activates fibroblast-like synoviocytes (FLS) inducing in a temporal order a constellation of genes, which perpetuate synovial inflammation. Although the molecular mechanisms regulating TNF-induced transcription are well characterized, lit...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Loupasakis, Konstantinos, Kuo, David, Sokhi, Upneet K., Sohn, Christopher, Syracuse, Bethany, Giannopoulou, Eugenia G., Park, Sung Ho, Kang, Hyelim, Rätsch, Gunnar, Ivashkiv, Lionel B., Kalliolias, George D.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510804/
https://ncbi.nlm.nih.gov/pubmed/28708839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179762
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