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Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells
Langerhans cell histiocytosis (LCH) and the non-LCH neoplasm Erdheim-Chester disease (ECD) are heterogeneous neoplastic disorders marked by infiltration of pathologic macrophage-, dendritic cell–, or monocyte-derived cells in tissues driven by recurrent mutations activating MAPK signaling. Although...
Shranjeno v:
| izdano v: | Blood |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510787/ https://ncbi.nlm.nih.gov/pubmed/28566492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-12-757377 |
| Oznake: |
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