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JAK2 inhibitors for myeloproliferative neoplasms: what is next?

Since its approval in 2011, the Janus kinase 1/2 (JAK1/2) inhibitor ruxolitinib has evolved to become the centerpiece of therapy for myelofibrosis (MF), and its use in patients with hydroxyurea resistant or intolerant polycythemia vera (PV) is steadily increasing. Several other JAK2 inhibitors have...

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Foilsithe in:Blood
Main Authors: Bose, Prithviraj, Verstovsek, Srdan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510786/
https://ncbi.nlm.nih.gov/pubmed/28500170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-04-742288
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