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JAK2 inhibitors for myeloproliferative neoplasms: what is next?

Since its approval in 2011, the Janus kinase 1/2 (JAK1/2) inhibitor ruxolitinib has evolved to become the centerpiece of therapy for myelofibrosis (MF), and its use in patients with hydroxyurea resistant or intolerant polycythemia vera (PV) is steadily increasing. Several other JAK2 inhibitors have...

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Publicado en:Blood
Autores principales: Bose, Prithviraj, Verstovsek, Srdan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510786/
https://ncbi.nlm.nih.gov/pubmed/28500170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-04-742288
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