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Catch Bonds at T Cell Interfaces: Impact of Surface Reorganization and Membrane Fluctuations

Catch bonds are characterized by average lifetimes that initially increase with increasing tensile force. Recently, they have been implicated in T cell activation, where small numbers of antigenic receptor-ligand bonds at a cell-cell interface can stimulate a T cell. Here, we use computational metho...

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Publicat a:Biophys J
Autors principals: Pullen, Robert H., Abel, Steven M.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510709/
https://ncbi.nlm.nih.gov/pubmed/28700910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.023
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