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Synucleins have multiple effects on presynaptic architecture

Synucleins (α, β, γ-synuclein) are a family of abundant presynaptic proteins. α-Synuclein is causally linked to the pathogenesis of Parkinson disease (PD). In an effort to define their physiological and pathological function(s), we investigated the effects of deleting synucleins and overexpressing α...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Vargas, Karina J., Schrod, Nikolas, Davis, Taylor, Fernandez-Busnadiego, Ruben, Taguchi, Yumiko V., Laugks, Ulrike, Lucic, Vladan, Chandra, Sreeganga S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510332/
https://ncbi.nlm.nih.gov/pubmed/28052246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.023
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