Cytochrome P450‐mediated interaction between perazine and risperidone: implications for antipsychotic polypharmacy

BACKGROUND: Although clinically widespread, scientific evidence for antipsychotic polypharmacy is still limited. Combining different drugs increases the potential for drug–drug interactions, enhancing the risk of adverse drug reactions. We aimed to unravel the potential pharmacokinetic interactions...

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發表在:Br J Clin Pharmacol
Main Authors: Paulzen, Michael, Haen, Ekkehard, Hiemke, Christoph, Stegmann, Benedikt, Lammertz, Sarah E., Gründer, Gerhard, Schoretsanitis, Georgios
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
主題:
Pharmacokinetics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510064/
https://ncbi.nlm.nih.gov/pubmed/28160505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13255
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