Cytochrome P450‐mediated interaction between perazine and risperidone: implications for antipsychotic polypharmacy

BACKGROUND: Although clinically widespread, scientific evidence for antipsychotic polypharmacy is still limited. Combining different drugs increases the potential for drug–drug interactions, enhancing the risk of adverse drug reactions. We aimed to unravel the potential pharmacokinetic interactions...

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Detalles Bibliográficos
Publicado en:Br J Clin Pharmacol
Main Authors: Paulzen, Michael, Haen, Ekkehard, Hiemke, Christoph, Stegmann, Benedikt, Lammertz, Sarah E., Gründer, Gerhard, Schoretsanitis, Georgios
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Pharmacokinetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510064/
https://ncbi.nlm.nih.gov/pubmed/28160505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13255
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