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The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells

LMNA gene encodes for nuclear intermediate filament proteins lamin A/C. Mutations in this gene lead to a spectrum of genetic disorders, collectively referred to as laminopathies. Lamin A/C are widely expressed in most differentiated somatic cells but not in early embryos and some undifferentiated ce...

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Detalhes bibliográficos
Publicado no:Chromosoma
Main Authors: Piekarowicz, Katarzyna, Machowska, Magdalena, Dratkiewicz, Ewelina, Lorek, Daria, Madej-Pilarczyk, Agnieszka, Rzepecki, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509783/
https://ncbi.nlm.nih.gov/pubmed/27534416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-016-0610-9
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