Suppressed autophagic response underlies augmentation of renal ischemia/reperfusion injury by type 2 diabetes

Diabetes mellitus is a major risk factor for acute kidney injury (AKI). Here, we hypothesized that suppression of autophagic response underlies aggravation of renal ischemia/reperfusion (I/R) injury by type 2 diabetes mellitus (T2DM). In OLETF, a rat model of T2DM, and its non-diabetic control, LETO...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Muratsubaki, Shingo, Kuno, Atsushi, Tanno, Masaya, Miki, Takayuki, Yano, Toshiyuki, Sugawara, Hirohito, Shibata, Satoru, Abe, Koki, Ishikawa, Satoko, Ohno, Kouhei, Kimura, Yukishige, Tatekoshi, Yuki, Nakata, Kei, Ohwada, Wataru, Mizuno, Masashi, Miura, Tetsuji
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509657/
https://ncbi.nlm.nih.gov/pubmed/28706237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05667-5
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