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Improved Measurement of Brain Phenylalanine and Tyrosine Related to Neuropsychological Functioning in Phenylketonuria

Introduction: Researchers hypothesized that in phenylketonuria (PKU) high brain phenylalanine (Phe) levels and low brain tyrosine (Tyr) levels affect neuropsychological functioning. However, traditional magnetic resonance spectroscopy (MRS) yielded uncertain results of brain Phe and could not adequa...

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Detalhes bibliográficos
Publicado no:JIMD Rep
Main Authors: Waisbren, Susan E., Prabhu, Sanjay P., Greenstein, Patricia, Petty, Carter, Schomer, Donald, Anastasoaie, Vera, Charette, Kalin, Rodriguez, Daniel, Merugumala, Sai, Lin, Alexander P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509554/
https://ncbi.nlm.nih.gov/pubmed/27677920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2016_11
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