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Phenylketonuria. The in vivo hydroxylation rate of phenylalanine into tyrosine is decreased.

In phenylketonuria (PKU), the enzyme phenylalanine hydroxylase is deficient, resulting in a decreased conversion of phenylalanine (Phe) into tyrosine (Tyr). The severity of the disease is expressed as the tolerance for Phe at 5 yr of age. In PKU patients it is assumed that the decreased conversion o...

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Detalhes bibliográficos
Main Authors: van Spronsen, F J, Reijngoud, D J, Smit, G P, Nagel, G T, Stellaard, F, Berger, R, Heymans, H S
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508879/
https://ncbi.nlm.nih.gov/pubmed/9637722
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