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Phenylketonuria. The in vivo hydroxylation rate of phenylalanine into tyrosine is decreased.
In phenylketonuria (PKU), the enzyme phenylalanine hydroxylase is deficient, resulting in a decreased conversion of phenylalanine (Phe) into tyrosine (Tyr). The severity of the disease is expressed as the tolerance for Phe at 5 yr of age. In PKU patients it is assumed that the decreased conversion o...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9637722/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI737 |
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