MUC1-C INTEGRATES PD-L1 INDUCTION WITH REPRESSION OF IMMUNE EFFECTORS IN NON-SMALL CELL LUNG CANCER

Immunotherapeutic approaches, particularly PD-1/PD-L1 blockade, have improved the treatment of non-small cell lung cancer (NSCLC), supporting the premise that evasion of immune destruction is of importance for NSCLC progression. However, the signals responsible for upregulation of PD-L1 in NSCLC cel...

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Bouillez, Audrey, Rajabi, Hasan, Jin, Caining, Samur, Mehmet, Tagde, Ashujit, Alam, Maroof, Hiraki, Masayuki, Maeda, Takahiro, Hu, Xiufeng, Adeegbe, Dennis, Kharbanda, Surender, Wong, Kwok-Kin, Kufe, Donald
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509481/
https://ncbi.nlm.nih.gov/pubmed/28288138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.47
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