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On-chip human microvasculature assay for visualization and quantitation of tumor cell extravasation dynamics

Distant metastasis, which results in >90% of cancer related deaths, is enabled by hematogenous dissemination of tumor cells via the circulation. This requires the completion of a sequence of complex steps including transit, initial arrest, extravasation, survival and proliferation. Increased unde...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Chen, Michelle B., Whisler, Jordan A., Fröse, Julia, Yu, Cathy, Shin, Yoojin, Kamm, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509465/
https://ncbi.nlm.nih.gov/pubmed/28358393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.018
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