Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress

Aging is commonly associated with chronic low-grade inflammation and hypertension but it is unknown whether a cause-effect relationship exists between them. We compared the sensitivity of young adult (8-12 w) and aged (23-31 mo) male C57Bl6J mice to develop hypertension in response to a slow-pressor...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Dinh, Quynh Nhu, Drummond, Grant R., Kemp-Harper, Barbara K., Diep, Henry, Silva, T. Michael De, Kim, Hyun Ah, Vinh, Antony, Robertson, Avril A.B., Cooper, Matthew A., Mansell, Ashley, Chrissobolis, Sophocles, Sobey, Christopher G.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509458/
https://ncbi.nlm.nih.gov/pubmed/28659507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101255
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