Angiotensin II Activates MCP-1 and Induces Cardiac Hypertrophy and Dysfunction via Toll-like Receptor 4

AIM: Angiotensin II (AngII) produces reactive oxygen species (ROS), thus contributing to the development of cardiac hypertrophy and subsequent heart failure, and stimulates the expression of monocyte chemoattractant protein-1 (MCP-1). In addition, Toll-like receptor 4 (TLR4) is involved in the upreg...

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Detalhes bibliográficos
Publicado no:J Atheroscler Thromb
Main Authors: Matsuda, Susumu, Umemoto, Seiji, Yoshimura, Koichi, Itoh, Shinichi, Murata, Tomoaki, Fukai, Tohru, Matsuzaki, Masunori
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509415/
https://ncbi.nlm.nih.gov/pubmed/25752363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.27292
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