Mice lacking the Cβ subunit of PKA are resistant to angiotensin II-induced cardiac hypertrophy and dysfunction

BACKGROUND: PKA is a ubiquitous, multi-subunit cellular kinase that regulates a number of different physiological responses in response to cAMP, including metabolism, cell division, and cardiac function. Numerous studies have implicated altered PKA signaling in cardiac dysfunction. Recently, it has...

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Hlavní autoři: Enns, Linda C, Bible, Kenneth L, Emond, Mary J, Ladiges, Warren C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993729/
https://ncbi.nlm.nih.gov/pubmed/21080942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-307
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