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Investigation of IVS14+1G>A polymorphism of DPYD gene in a group of Bosnian patients treated with 5-fluorouracil and capecitabine
Adverse drug reactions still pose an important clinical problem. Dihydropyrimidine dehydrogenase (DPD) is an enzyme that regulates 5-FU quantities available for anabolic processes and hence affects its pharmacokinetics, toxicity and efficacy. There are several studies describing a hereditary (pharma...
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| Publicado no: | Bosn J Basic Med Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509399/ https://ncbi.nlm.nih.gov/pubmed/20507294 |
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