Reduced susceptibility of clinical strains of Mycobacterium tuberculosis to reactive nitrogen species promotes survival in activated macrophages

BACKGROUND: Drugs such as isoniazid (INH) and pretomanid (PRT), used against Mycobacterium tuberculosis are active partly through generation of reactive nitrogen species (RNS). The aim of this study was to explore variability in intracellular susceptibility to nitric oxide (NO) in clinical strains o...

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Vydáno v:PLoS One
Hlavní autoři: Idh, Jonna, Andersson, Blanka, Lerm, Maria, Raffetseder, Johanna, Eklund, Daniel, Woksepp, Hanna, Werngren, Jim, Mansjö, Mikael, Sundqvist, Tommy, Stendahl, Olle, Schön, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509328/
https://ncbi.nlm.nih.gov/pubmed/28704501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181221
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