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PTCH1 is a reliable marker for predicting imatinib response in chronic myeloid leukemia patients in chronic phase

Patched homolog 1 gene (PTCH1) expression and the ratio of PTCH1 to Smoothened (SMO) expression have been proposed as prognostic markers of the response of chronic myeloid leukemia (CML) patients to imatinib. We compared these measurements in a realistic cohort of 101 patients with CML in chronic ph...

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הוצא לאור ב:PLoS One
Main Authors: Alonso-Dominguez, Juan M., Casado, Luis Felipe, Anguita, Eduardo, Gomez-Casares, Maria Teresa, Buño, Ismael, Ferrer-Marín, Francisca, Arenas, Alicia, Del Orbe, Rafael, Ayala, Rosa, Llamas, Pilar, Salgado, Rocio N., Osorio, Santiago, Sanchez-Godoy, Pedro, Burgaleta, Carmen, Mahíllo-Fernández, Ignacio, Garcia-Gutierrez, Valentin, Steegmann, Juan Luis, Martinez-Lopez, Joaquín
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509313/
https://ncbi.nlm.nih.gov/pubmed/28704552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181366
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