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Higher Serum Alanine Transaminase Levels in Male Urokinase-Type Plasminogen Activator-Transgenic Mice Are Associated With Improved Engraftment of Hepatocytes but not Liver Sinusoidal Endothelial Cells

The effects of sex on the degree of liver damage and human cell engraftment were investigated in immunodeficient urokinase-type plasminogen activator-transgenic (uPA-NOG) mice. Liver damage, measured by serum alanine transaminase (ALT) levels, was compared in male and female uPA-NOG mice of differen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Med
Hauptverfasser: Fomin, Marina E., Beyer, Ashley I., Publicover, Jean, Lu, Kai, Bakkour, Sonia, Simmons, Graham, Muench, Marcus O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cognizant Communication Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509021/
https://ncbi.nlm.nih.gov/pubmed/28713641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/215517916X693375
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