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Caspofungin increases fungal chitin and eosinophil and γδ T cell-dependent pathology in invasive aspergillosis

The polysaccharide-rich fungal cell wall provides pathogen-specific targets for antifungal therapy and distinct molecular patterns that stimulate protective or detrimental host immunity. The echinocandin antifungal caspofungin inhibits synthesis of cell wall β-1,3-glucan and is used for prophylactic...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Amarsaikhan, Nansalmaa, Sands, Ethan M., Shah, Anand, Abdolrasouli, Ali, Reed, Anna, Slaven, James E., Armstrong-James, Darius, Templeton, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508594/
https://ncbi.nlm.nih.gov/pubmed/28566368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700078
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