Eosinophils Are Recruited in Response to Chitin Exposure and Enhance Th2-Mediated Immune Pathology in Aspergillus fumigatus Infection

In patients infected with the fungus Aspergillus fumigatus, Th1 responses are considered protective, while Th2 responses are associated with increased morbidity and mortality. How host-pathogen interactions influence the development of these protective or detrimental immune responses is not clear. W...

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Autori principali: O'Dea, Evan M., Amarsaikhan, Nansalmaa, Li, Hongtao, Downey, Joshua, Steele, Emery, Van Dyken, Steven J., Locksley, Richard M., Templeton, Steven P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136210/
https://ncbi.nlm.nih.gov/pubmed/24842927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01990-14
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