Eosinophils Are Recruited in Response to Chitin Exposure and Enhance Th2-Mediated Immune Pathology in Aspergillus fumigatus Infection

In patients infected with the fungus Aspergillus fumigatus, Th1 responses are considered protective, while Th2 responses are associated with increased morbidity and mortality. How host-pathogen interactions influence the development of these protective or detrimental immune responses is not clear. W...

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Main Authors: O'Dea, Evan M., Amarsaikhan, Nansalmaa, Li, Hongtao, Downey, Joshua, Steele, Emery, Van Dyken, Steven J., Locksley, Richard M., Templeton, Steven P.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
主題:
Fungal and Parasitic Infections
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136210/
https://ncbi.nlm.nih.gov/pubmed/24842927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01990-14
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