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Regulation of Cl- transport in T84 cell clones expressing a mutant regulatory subunit of cAMP-dependent protein kinase.

Cl- channels in the apical membranes of salt-secreting epithelia are activated by both cAMP and Ca2+ second-messenger systems, and dysfunctions in their hormonal regulation have been demonstrated in patients with cystic fibrosis. We have transfected the epithelial cell line T84 with an expression ve...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Rogers, K V, Goldman, P S, Frizzell, R A, McKnight, G S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.22.8975
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