Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is the most common neurosurgical treatment for Parkinson's disease motor symptoms. In preclinical models, STN DBS provides neuroprotection for substantia nigra (SN) dopamine neurons and increases BDNF in the nigrostriatal system and...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Fischer, D. Luke, Kemp, Christopher J., Cole-Strauss, Allyson, Polinski, Nicole K., Paumier, Katrina L., Lipton, Jack W., Steece-Collier, Kathy, Collier, Timothy J., Buhlinger, Daniel J., Sortwell, Caryl E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508259/
https://ncbi.nlm.nih.gov/pubmed/28607168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2060-16.2017
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