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Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation

Browning of subcutaneous white fat (iWAT) involves several reprograming events, but the underlying mechanisms are incompletely understood. Here we show that the transcription factor Hlx is selectively expressed in brown adipose tissue (BAT) and iWAT, and is translationally upregulated by β3-adrenerg...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Huang, Lei, Pan, Dongning, Chen, Qingbo, Zhu, Lihua J., Ou, Jianhong, Wabitsch, Martin, Wang, Yong-Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507986/
https://ncbi.nlm.nih.gov/pubmed/28701693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00098-2
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