Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

The imminent threat of viral epidemics and pandemics dictates a need for therapeutic approaches that target viral pathology irrespective of the infecting strain. Reactive oxygen species are ancient processes that protect plants, fungi and animals against invading pathogens including bacteria. Howeve...

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Udgivet i:Nat Commun
Main Authors: To, Eunice E., Vlahos, Ross, Luong, Raymond, Halls, Michelle L., Reading, Patrick C., King, Paul T., Chan, Christopher, Drummond, Grant R., Sobey, Christopher G., Broughton, Brad R. S., Starkey, Malcolm R., van der Sluis, Renee, Lewin, Sharon R., Bozinovski, Steven, O’Neill, Luke A. J., Quach, Tim, Porter, Christopher J. H., Brooks, Doug A., O’Leary, John J., Selemidis, Stavros
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507984/
https://ncbi.nlm.nih.gov/pubmed/28701733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00057-x
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