Transient Depletion of CD169(+) Cells Contributes to Impaired Early Protection and Effector CD8(+) T Cell Recruitment against Mucosal Respiratory Syncytial Virus Infection

Respiratory syncytial virus (RSV) is a major cause of respiratory viral infections in infants and children. Alveolar macrophages (AMs) play a crucial role in combatting airborne pathogens, strongly express CD169, and are localized in the lung alveoli. Therefore, we used CD169-diphtheria toxin recept...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Oh, Dong Sun, Oh, Ji Eun, Jung, Hi Eun, Lee, Heung Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507946/
https://ncbi.nlm.nih.gov/pubmed/28751894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00819
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