Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

Lamina propria (LP) macrophages are constantly exposed to commensal bacteria, and are refractory to those antigens in an interleukin (IL)-10-dependent fashion. However, the mechanisms that discriminate hazardous invasion by bacteria from peaceful co-existence with them remain elusive. Here we show t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Asano, Kenichi, Takahashi, Naomichi, Ushiki, Mikiko, Monya, Misa, Aihara, Fumiaki, Kuboki, Erika, Moriyama, Shigetaka, Iida, Mayumi, Kitamura, Hiroshi, Qiu, Chun-Hong, Watanabe, Takashi, Tanaka, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518321/
https://ncbi.nlm.nih.gov/pubmed/26193821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8802
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