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Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

Lamina propria (LP) macrophages are constantly exposed to commensal bacteria, and are refractory to those antigens in an interleukin (IL)-10-dependent fashion. However, the mechanisms that discriminate hazardous invasion by bacteria from peaceful co-existence with them remain elusive. Here we show t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Asano, Kenichi, Takahashi, Naomichi, Ushiki, Mikiko, Monya, Misa, Aihara, Fumiaki, Kuboki, Erika, Moriyama, Shigetaka, Iida, Mayumi, Kitamura, Hiroshi, Qiu, Chun-Hong, Watanabe, Takashi, Tanaka, Masato
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Pub. Group 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518321/
https://ncbi.nlm.nih.gov/pubmed/26193821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8802
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