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Systematic discovery of genetic modulation by Jumonji histone demethylases in Drosophila

Jumonji (JmjC) domain proteins influence gene expression and chromatin organization by way of histone demethylation, which provides a means to regulate the activity of genes across the genome. JmjC proteins have been associated with many human diseases including various cancers, developmental and ne...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Shalaby, Nevine A., Sayed, Raheel, Zhang, Qiao, Scoggin, Shane, Eliazer, Susan, Rothenfluh, Adrian, Buszczak, Michael
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507883/
https://ncbi.nlm.nih.gov/pubmed/28701701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05004-w
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