Protein kinase C beta II upregulates intercellular adhesion molecule-1 via mitochondrial activation in cultured endothelial cells

Activation of protein kinase C (PKC) is closely linked with endothelial dysfunction. However, the effect of PKCβII on endothelial dysfunction has not been characterized in cultured endothelial cells. Here, using adenoviral PKCβII gene transfer and pharmacological inhibitors, the role of PKCβII on en...

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Pubblicato in:Korean J Physiol Pharmacol
Autori principali: Joo, Hee Kyoung, Lee, Yu Ran, Choi, Sunga, Park, Myoung Soo, Kang, Gun, Kim, Cuk-Seong, Jeon, Byeong Hwa
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Physiological Society and The Korean Society of Pharmacology 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507776/
https://ncbi.nlm.nih.gov/pubmed/28706451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.4.377
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