Trichostatin A Modulates Angiotensin II-induced Vasoconstriction and Blood Pressure Via Inhibition of p66shc Activation

Histone deacetylase (HDAC) has been recognized as a potentially useful therapeutic target for cardiovascular disorders. However, the effect of the HDAC inhibitor, trichostatin A (TSA), on vasoreactivity and hypertension remains unknown. We performed aortic coarctation at the inter-renal level in rat...

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Detalhes bibliográficos
Publicado no:Korean J Physiol Pharmacol
Main Authors: Kang, Gun, Lee, Yu Ran, Joo, Hee Kyoung, Park, Myoung Soo, Kim, Cuk-Seong, Choi, Sunga, Jeon, Byeong Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553407/
https://ncbi.nlm.nih.gov/pubmed/26330760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2015.19.5.467
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