Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine (1)H-NMR spectroscopy-based metabolic phenotyping in an isogenic C57BL/6J mouse population (n = 50) and show t...

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Udgivet i:Cell Rep
Main Authors: Dumas, Marc-Emmanuel, Rothwell, Alice R., Hoyles, Lesley, Aranias, Thomas, Chilloux, Julien, Calderari, Sophie, Noll, Elisa M., Péan, Noémie, Boulangé, Claire L., Blancher, Christine, Barton, Richard H., Gu, Quan, Fearnside, Jane F., Deshayes, Chloé, Hue, Christophe, Scott, James, Nicholson, Jeremy K., Gauguier, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507771/
https://ncbi.nlm.nih.gov/pubmed/28683308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.039
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