Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine (1)H-NMR spectroscopy-based metabolic phenotyping in an isogenic C57BL/6J mouse population (n = 50) and show t...

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Опубликовано в: :Cell Rep
Главные авторы: Dumas, Marc-Emmanuel, Rothwell, Alice R., Hoyles, Lesley, Aranias, Thomas, Chilloux, Julien, Calderari, Sophie, Noll, Elisa M., Péan, Noémie, Boulangé, Claire L., Blancher, Christine, Barton, Richard H., Gu, Quan, Fearnside, Jane F., Deshayes, Chloé, Hue, Christophe, Scott, James, Nicholson, Jeremy K., Gauguier, Dominique
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507771/
https://ncbi.nlm.nih.gov/pubmed/28683308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.039
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