ANK1 is up-regulated in laser captured microglia in Alzheimer’s brain; the importance of addressing cellular heterogeneity

Recent epigenetic association studies have identified a new gene, ANK1, in the pathogenesis of Alzheimer’s disease (AD). Although strong associations were observed, brain homogenates were used to generate the data, introducing complications because of the range of cell types analyzed. In order to ad...

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Spremljeno u:
Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Mastroeni, Diego, Sekar, Shobana, Nolz, Jennifer, Delvaux, Elaine, Lunnon, Katie, Mill, Jonathan, Liang, Winnie S., Coleman, Paul D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507536/
https://ncbi.nlm.nih.gov/pubmed/28700589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177814
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