ANK1 is up-regulated in laser captured microglia in Alzheimer’s brain; the importance of addressing cellular heterogeneity

Recent epigenetic association studies have identified a new gene, ANK1, in the pathogenesis of Alzheimer’s disease (AD). Although strong associations were observed, brain homogenates were used to generate the data, introducing complications because of the range of cell types analyzed. In order to ad...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Mastroeni, Diego, Sekar, Shobana, Nolz, Jennifer, Delvaux, Elaine, Lunnon, Katie, Mill, Jonathan, Liang, Winnie S., Coleman, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507536/
https://ncbi.nlm.nih.gov/pubmed/28700589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177814
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