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Real sequence effects on the search dynamics of transcription factors on DNA

Recent experiments show that transcription factors (TFs) indeed use the facilitated diffusion mechanism to locate their target sequences on DNA in living bacteria cells: TFs alternate between sliding motion along DNA and relocation events through the cytoplasm. From simulations and theoretical analy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bauer, Maximilian, Rasmussen, Emil S., Lomholt, Michael A., Metzler, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507490/
https://ncbi.nlm.nih.gov/pubmed/26154484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10072
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