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Implementation of a loss-of-function system to determine growth and stress-associated mutagenesis in Bacillus subtilis
A forward mutagenesis system based on the acquisition of mutations that inactivate the thymidylate synthase gene (TMS) and confer a trimethoprim resistant (Tmp(r)) phenotype was developed and utilized to study transcription-mediated mutagenesis (TMM). In addition to thyA, Bacillus subtilis possesses...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507404/ https://ncbi.nlm.nih.gov/pubmed/28700593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179625 |
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