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Small-molecule inhibition of pyruvate phosphate dikinase targeting the nucleotide binding site

Pyruvate phosphate dikinase (PPDK) is an essential enzyme of C(4) photosynthesis in plants, catalyzing the ATP-driven conversion of pyruvate to phosphoenolpyruvate (PEP). It is further used by some bacteria and unicellular protists in the reverse, ATP-forming direction. Many weed species use C(4) ph...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Minges, Alexander, Groth, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507339/
https://ncbi.nlm.nih.gov/pubmed/28700696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181139
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