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Structural intermediates and directionality of the swiveling motion of Pyruvate Phosphate Dikinase

Pyruvate phosphate dikinase (PPDK) is a vital enzyme in cellular energy metabolism catalyzing the ATP- and P(i)-dependent formation of phosphoenolpyruvate from pyruvate in C(4) -plants, but the reverse reaction forming ATP in bacteria and protozoa. The multi-domain enzyme is considered an efficient...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Minges, Alexander, Ciupka, Daniel, Winkler, Christian, Höppner, Astrid, Gohlke, Holger, Groth, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371819/
https://ncbi.nlm.nih.gov/pubmed/28358005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45389
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