Acquired Senescent T-Cell Phenotype Correlates with Clinical Severity in GATA Binding Protein 2-Deficient Patients

GATA binding protein 2 (GATA2) deficiency is a rare disorder of hematopoiesis, lymphatics, and immunity caused by spontaneous or autosomal dominant mutations in the GATA2 gene. Clinical manifestations range from neutropenia, lymphedema, deafness, to severe viral and mycobacterial infections, bone ma...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ruiz-García, Raquel, Rodríguez-Vigil, Carmen, Marco, Francisco Manuel, Gallego-Bustos, Fernando, Castro-Panete, María José, Diez-Alonso, Laura, Muñoz-Ruiz, Carlos, Ruiz-Contreras, Jesús, Paz-Artal, Estela, González-Granado, Luis Ignacio, Allende, Luis Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506090/
https://ncbi.nlm.nih.gov/pubmed/28747912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00802
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