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Evaluation of Osteogenesis and Angiogenesis of Icariin in Local Controlled Release and Systemic Delivery for Calvarial Defect in Ovariectomized Rats

Typically, bone regenerative medicine is applied to repair bone defects in patients with osteoporosis. Meanwhile, there is an urgent need to develop safe and cheap drugs that induce bone formation. Icariin, which is reported to promote the osteogenesis of stem cells in vitro, is the main active comp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Yuqiong, Cao, LingYan, Xia, Lunguo, Wu, Qianju, Wang, Jie, Wang, Xiao, Xu, Lianyi, Zhou, Yuning, Xu, Yuanjin, Jiang, Xinquan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505963/
https://ncbi.nlm.nih.gov/pubmed/28698566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05392-z
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