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Gene-gene and gene-environment interactions influence platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients

Platinum-based chemotherapy is a major therapeutic regimen of lung cancer. Various single nucleotide polymorphisms (SNPs) reported were associated with platinum-based chemotherapy response and drug toxicity. However, neither of the studies explored this association from SNP-SNP interaction perspecti...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Cui, Jia-Jia, Wang, Lei-Yun, Zhu, Tao, Gong, Wei-Jing, Zhou, Hong-Hao, Liu, Zhao-Qian, Yin, Ji-Ye
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505954/
https://ncbi.nlm.nih.gov/pubmed/28698656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05246-8
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