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Anesthetic synergy between two n-alkanes

OBJECTIVE: N-butane and n-pentane each can produce general anesthesia. Both compounds potentiate GABA(A) receptor function, but only butane inhibits NMDA receptors. It was hypothesized that butane and pentane would exhibit anesthetic synergy due to their different actions on ligand-gated ion channel...

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Bibliographic Details
Published in:Vet Anaesth Analg
Main Authors: Brosnan, Robert J, Fukushima, Fabíola B, Pham, Trung L
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505817/
https://ncbi.nlm.nih.gov/pubmed/28583773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaa.2016.07.003
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