TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs

Proinflammatory signals promote prostate tumorigenesis and progression, but their origins and downstream effects remain unclear. We recently demonstrated that the expression of an innate immune receptor, TLR9, by prostate cancer cells is critical for their tumor-propagating potential. We investigate...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Won, Haejung, Moreira, Dayson, Gao, Chan, Duttagupta, Priyanka, Zhao, Xingli, Manuel, Edwin, Diamond, Don, Yuan, Yate-Ching, Liu, Zheng, Jones, Jeremy, D’Apuzzo, Massimo, Pal, Sumanta, Kortylewski, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2017
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505743/
https://ncbi.nlm.nih.gov/pubmed/28533357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3MA1016-451RR
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