Pilot study of large-scale production of mutant pigs by ENU mutagenesis

N-ethyl-N-nitrosourea (ENU) mutagenesis is a powerful tool to generate mutants on a large scale efficiently, and to discover genes with novel functions at the whole-genome level in Caenorhabditis elegans, flies, zebrafish and mice, but it has never been tried in large model animals. We describe a su...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hai, Tang, Cao, Chunwei, Shang, Haitao, Guo, Weiwei, Mu, Yanshuang, Yang, Shulin, Zhang, Ying, Zheng, Qiantao, Zhang, Tao, Wang, Xianlong, Liu, Yu, Kong, Qingran, Li, Kui, Wang, Dayu, Qi, Meng, Hong, Qianlong, Zhang, Rui, Wang, Xiupeng, Jia, Qitao, Wang, Xiao, Qin, Guosong, Li, Yongshun, Luo, Ailing, Jin, Weiwu, Yao, Jing, Huang, Jiaojiao, Zhang, Hongyong, Li, Menghua, Xie, Xiangmo, Zheng, Xuejuan, Guo, Kenan, Wang, Qinghua, Zhang, Shibin, Li, Liang, Xie, Fei, Zhang, Yu, Weng, Xiaogang, Yin, Zhi, Hu, Kui, Cong, Yimei, Zheng, Peng, Zou, Hailong, Xin, Leilei, Xia, Jihan, Ruan, Jinxue, Li, Hegang, Zhao, Weiming, Yuan, Jing, Liu, Zizhan, Gu, Weiwang, Li, Ming, Wang, Yong, Wang, Hongmei, Yang, Shiming, Liu, Zhonghua, Wei, Hong, Zhao, Jianguo, Zhou, Qi, Meng, Anming
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505698/
https://ncbi.nlm.nih.gov/pubmed/28639938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26248
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